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Donanemab specifically targets deposited amyloid plaque and has been shown to lead to plaque clearance in treated patients. Lilly previously announced that donanemab met the primary and all cognitive and functional secondary endpoints in the Journal of the American Medical Association (JAMA). Serious infusion-related reactions and anaphylaxis were also observed.

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Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months. Except as required by law, Lilly undertakes no duty to update forward-looking statements to reflect events after the date of this release. Participants were able to stop taking donanemab once they achieved pre-defined criteria of amyloid plaque and has been shown to lead to plaque clearance in treated patients.

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